Human papilloma virus (HPV) infection is associated with HIV-1 infection and AIDS in HIV-infected adult patients from Zaria, Northern Nigeria

Human papilloma virus (HPV) is the most common sexually transmitted virus and it is estimated that about 75% of sexually active women and men will acquire a genital HPV infection at some time.[1] There is an advance clinical association between HPV and HIV-1[2,3] and it has been suggested that HPV may also facilitate progression of HIV-1 disease by recruitment of HIV target cells, such as CD4+ T-cells and macrophages, into the site of active HPV infection, and by inducing the production of inflammatory cytokines, including IL-6, TNF45; and IL-1, which in turn induce the replication and reverse transcription of HIV-1 [4].